A Review of Cardiac and Non-Cardiac Causes of Troponin Elevation and Clinical Relevance Part I: Cardiac Causes
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چکیده
Cardiac troponin T (cTnT) and troponin I (cTnI) are cardiac regulatory proteins that control the calcium mediated interaction between actin and myosin [1]. The troponin complex consists of three subunits: troponin C, troponin I, and troponin T. This complex is located on the myofibrillar thin (actin) filament of striated (skeletal and cardiac) muscle. The cardiac isoforms troponin T and I are only expressed in cardiac muscle [1].
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A Review of Cardiac and Non-Cardiac Causes of Troponin Elevation and Clinical Relevance Part I: Cardiac Causes
Cardiac troponin T (cTnT) and troponin I (cTnI) are cardiac regulatory proteins that control the calcium mediated interaction between actin and myosin [1]. The troponin complex consists of three subunits: troponin C, troponin I, and troponin T. This complex is located on the myofibrillar thin (actin) filament of striated (skeletal and cardiac) muscle. The cardiac isoforms troponin T and I are o...
متن کاملA Review of Cardiac and Non-Cardiac Causes of Troponin Elevation and Clinical Relevance Part II Non Cardiac Causes
Not every troponin elevation is due to acute myocardial infarction (MI). Several other clinical cardiac conditions such as arrhythmias, cardiac ablation, cardiac contusion, infiltrative cardiac disorders, defibrillation shocks and many other conditions as listed in our previous article can lead to increase troponins. Elevated cardiac troponins have also been commonly found in non-cardiac condit...
متن کاملA Review of Cardiac and Non-Cardia Causes of Troponin Elevation and Clinical Relevance Part II Non Cardiac Causes
Not every troponin elevation is due to acute myocardial infarction (MI). Several other clinical cardiac conditions such as arrhythmias, cardiac ablation, cardiac contusion, infiltrative cardiac disorders, defibrillation shocks and many other conditions as listed in our previous article can lead to increase troponins. Elevated cardiac troponins have also been commonly found in non-cardiac condit...
متن کاملA Review of Cardiac and Non-Cardia Causes of Troponin Elevation and Clinical Relevance Part II Non Cardiac Causes
Not every troponin elevation is due to acute myocardial infarction (MI). Several other clinical cardiac conditions such as arrhythmias, cardiac ablation, cardiac contusion, infiltrative cardiac disorders, defibrillation shocks and many other conditions as listed in our previous article can lead to increase troponins. Elevated cardiac troponins have also been commonly found in non-cardiac condit...
متن کاملSertraline alters level of adenosine deaminase activity, oxidative stress markers and cardiac biomarkers (homocysteine cardiac troponin I) in rats
The aim of this study is whether oxidative stress markers, homocysteine (Hcy), cardiac troponin I (cTnI) and the activity of adenosine deaminase (ADA) alter following administration of different doses of sertraline. Sixty male Wistar rats were assigned into four groups. Sertraline at doses of 20, 40 and 80 mg / kg / day) were administered to three groups through gastric gavage for 90 days. The ...
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